KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SHD
All Species:
6.36
Human Site:
S222
Identified Species:
17.5
UniProt:
Q96IW2
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96IW2
NP_064594.3
340
38264
S222
L
R
R
P
P
P
R
S
P
Q
P
A
E
R
V
Chimpanzee
Pan troglodytes
XP_512284
340
38193
S222
L
R
R
P
P
P
R
S
P
Q
P
A
E
R
V
Rhesus Macaque
Macaca mulatta
XP_001101859
239
26986
P137
Q
R
V
M
S
E
L
P
G
R
G
V
Q
L
Y
Dog
Lupus familis
XP_538741
623
67323
P491
R
R
R
Q
L
R
A
P
G
G
G
F
K
P
I
Cat
Felis silvestris
Mouse
Mus musculus
O88834
343
38463
T216
Q
P
A
E
R
V
D
T
A
L
A
L
E
K
Q
Rat
Rattus norvegicus
NP_001101693
343
38828
T216
Q
P
A
E
R
V
D
T
A
L
A
L
E
K
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519012
207
23669
P105
A
E
R
E
Y
C
N
P
F
D
A
E
A
R
V
Chicken
Gallus gallus
XP_424863
331
38013
E228
I
D
P
T
V
P
L
E
K
Q
I
W
Y
H
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001038542
391
44295
P259
L
R
C
S
R
A
P
P
T
T
G
S
M
K
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
69.7
31.9
N.A.
77.2
74.3
N.A.
31.4
37.9
N.A.
53.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.7
69.7
40.7
N.A.
82.5
81.3
N.A.
42.6
58.5
N.A.
68.5
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
6.6
13.3
N.A.
6.6
6.6
N.A.
20
13.3
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
20
26.6
N.A.
20
20
N.A.
20
20
N.A.
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
0
23
0
0
12
12
0
23
0
34
23
12
0
0
% A
% Cys:
0
0
12
0
0
12
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
12
0
0
0
0
23
0
0
12
0
0
0
0
0
% D
% Glu:
0
12
0
34
0
12
0
12
0
0
0
12
45
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
12
0
0
12
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
23
12
34
0
0
0
12
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% H
% Ile:
12
0
0
0
0
0
0
0
0
0
12
0
0
0
12
% I
% Lys:
0
0
0
0
0
0
0
0
12
0
0
0
12
34
0
% K
% Leu:
34
0
0
0
12
0
23
0
0
23
0
23
0
12
12
% L
% Met:
0
0
0
12
0
0
0
0
0
0
0
0
12
0
0
% M
% Asn:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% N
% Pro:
0
23
12
23
23
34
12
45
23
0
23
0
0
12
0
% P
% Gln:
34
0
0
12
0
0
0
0
0
34
0
0
12
0
23
% Q
% Arg:
12
56
45
0
34
12
23
0
0
12
0
0
0
34
0
% R
% Ser:
0
0
0
12
12
0
0
23
0
0
0
12
0
0
0
% S
% Thr:
0
0
0
12
0
0
0
23
12
12
0
0
0
0
0
% T
% Val:
0
0
12
0
12
23
0
0
0
0
0
12
0
0
34
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
0
% W
% Tyr:
0
0
0
0
12
0
0
0
0
0
0
0
12
0
12
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _